Human Leukocyte antigen B27 (HLA- B27) belongs to a group of cell surface glycoproteins which are expressed on most nucleated human cells and platelets. It is a major histocompatibility complex (MHC) class I molecule. The presence of HLA – B27 is strongly associated with ankylosing spondylitis and some inflammatory disorders like Reiter’s syndrome, inflammatory bowel syndrome, etc. The binding ability of specific monoclonal antibodies to the antigenic determinants expressed by leucocytes on the surface forms the basis of this test. HLA-B 27 test is generally advised in patients suffering from joint pain where the diagnosis of ankylosing spondylitis is suspected. A positive test result indicates higher chances of developing this disease. Avail of the service by booking the HLA-B27 test online at an affordable rate, at your doorstep.
HLA-B27 is a protein found on white blood cells that helps the immune system identify harmful substances. It’s also the name of a blood test that checks for the presence of this protein.
What is HLA-B27 associated with?
Ankylosing spondylitis: An autoimmune disease that affects the spine. Most people with ankylosing spondylitis have the HLA-B27 gene, but many people with the gene never develop the disease.
Reactive arthritis: An autoimmune disease that affects the joints. 60–85% of patients with reactive arthritis are HLA-B27 positive.
Juvenile arthritis: An autoimmune disease that occurs in children.
How is the test performed?
The HLA-B27 test is a blood draw that’s usually taken from the arm.
A healthcare provider in a doctor’s office or a clinical lab administers the test.
The blood is collected in a tube and sent to a lab for analysis.
HLA-B27 prevalence
The prevalence of HLA-B27 varies between populations.
In the UK, HLA-B27 is present in 90–95% of patients with ankylosing spondylitis.
In the general population, 8 in every 100 people have the HLA-B27 gene variant.
₹2,090.00Original price was: ₹2,090.00.₹1,500.00Current price is: ₹1,500.00.
Homeostasis model assessment of insulin resistance (HOMA-IR) is a test that measures insulin resistance. It’s used in clinical practice and epidemiological studies to help identify people who may have type 2 diabetes.
How it’s calculated
HOMA-IR is calculated using fasting blood sugar and insulin levels
The formula is: Fasting serum insulin (μU/ml) × fasting plasma glucose (mmol l)/22.5
The threshold HOMA-IR level that indicates insulin resistance varies by study
What it’s used for
HOMA-IR is used to estimate insulin resistance, which is a risk factor for type 2 diabetes and cardiovascular disease
It’s also used to predict the risk of metabolic syndrome and inflammatory disease
Who it’s used for
HOMA-IR has been used in clinical and epidemiological studies of adults
It’s also been used in studies of adolescents
Other considerations
HOMA-IR is a biomarker for type 2 diabetes
The role of HOMA-IR in non-diabetics is less clear
HOMA-IR levels can vary depending on age, gender, and other factors
₹750.00Original price was: ₹750.00.₹700.00Current price is: ₹700.00.
Blood tests for hypertension measure levels of potassium, sodium, cholesterol, and glucose in your blood. They may also include a urinalysis and other tests.
Blood tests
Complete blood count: Checks your blood cell count
Blood chemistry: Measures levels of potassium, sodium, creatinine, and total cholesterol
Cholesterol test: Also known as a lipid profile, this test measures levels of HDL and non-HDL cholesterol
Blood sugar (glucose) test: Determines if you have diabetes
Aldosterone test: Measures the amount of aldosterone in your blood or urine
Urine tests
Urinalysis: Can reveal kidney or liver problems
Other tests
Kidney function tests: Check for kidney damage
Thyroid function tests: Check for thyroid issues
ECG (electrocardiogram): Checks your heart’s electrical activity
Blood pressure
Blood pressure is measured in millimeters of mercury (mm Hg). A reading of 130/80 mm Hg or higher is considered high blood pressure.
Preparation
Before a blood pressure test, you should avoid exercising, drinking coffee, or smoking cigarettes. You should also sit in a chair and relax for at least five minutes.
₹3,500.00Original price was: ₹3,500.00.₹3,000.00Current price is: ₹3,000.00.
