Description
| Method: | LC-MS / MS |
| Comment: | Measurement of plasma free metanephrines by LC-MS/MS is the test of first choice in diagnosis of Pheochromocytoma and Paraganglionomas because it has high diagnostic accuracy. |
| Price: | 6500.00 |
| Report: | Sample Wed / Sat by 9 am; Report Fri / Tue |
| Usage: | Metanephrines and Normetanephrines are elevated in catecholamine secreting tumors like Pheochromocytomas and in tumors derived from neural crest cells like Paraganglioma and Neuroblastoma. Measurement of plasma free metanephrines appears to be the best test for excluding Pheochromocytoma as the test’s sensitivity is approximately 96-99 % and offers specificity between 80-100 %. Tumoral production of 3-methoxytyramine is associated with presence of an underlying SDHB mutation and may be a biomarker of malignancy. Following patients with or without hypertension should be investigated for Pheochromocytoma: • Previous history of tumor • Adrenal incidentaloma • Hereditary predisposition |
| Doctor Specialty: | Physician, Oncologist |
| Disease: | Hypertension, Cancer |
| Components: | *Metanephrine Free *Normetanephrine Free *3-Methoxytyramine |
| Courier Charges: | |
| Home Collection: | Not Available |
| Department: | GENETIC |
| Pre Test Information: | Patient should strictly avoid drugs like Labetalol, Sotalol, Acetaminophen, Methyldopa, Antidepressants and agents like Ephedrine, Amphetamine, Nicotine and Caffeine etc. Avoid foods like banana, pineapple, nuts and cereals etc. at least 72 hours prior to sample collection. |