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CHROMOGRANIN A; CGA

Original price was: ₹5,500.00.Current price is: ₹5,000.00.

Chromogranin A (CgA), a protein produced by neuroendocrine cells, is a potential tumor marker, particularly for neuroendocrine tumors (NETs), and its levels in the blood can be measured to help with diagnosis, monitoring, and assessing treatment response, though it’s not a specific marker for NETs alone. 

Here’s a more detailed breakdown:
  • What it is:
    CgA is a glycoprotein, a type of protein, that is stored in the secretory granules of neuroendocrine cells and released when these cells are stimulated. 

  • Function:
    CgA, along with other chromogranins, is involved in the formation and regulation of dense-core granules, and it is believed to be important for the release of hormones and other molecules from these granules. 

  • As a tumor marker:
    CgA is a circulating biomarker that can be measured in the blood, and elevated levels are often associated with neuroendocrine tumors, including those in the gastro-entero-pancreatic (GEP) region. 

  • Uses:
    • Diagnosis: CgA tests can be used to help detect and diagnose NETs, especially functional and advanced NETs. 
    • Monitoring: CgA levels are commonly used to monitor the progression of NETs and assess the effectiveness of treatment. 
    • Prognosis: CgA levels may be correlated with the disease extent of GEP-NETs and may also be used to predict survival and treatment response in advanced NET patients. 
  • Limitations:
    • Lack of Specificity: CgA can be elevated in other non-cancer conditions, such as renal failure, liver disease, and inflammatory conditions, making it less specific as a tumor marker. 
    • Non-NET Cancers: CgA levels can also be elevated in some non-NET cancers, including breast, thyroid, pancreatic, and prostate cancers. 
    • Other Factors: Certain factors, such as food and medications, can also interfere with CgA levels. 
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Description

Method: TRACE
Comment:
Price: 5500.00
Report: Sample Tue / Fri by 11 am; Report Same day
Usage: Chromogranin A is the first line test for diagnosing Carcinoid tumors. It is used as a followup test for treated cases of Carcinoid tumors. It is useful as an adjunct in the diagnosis of other Neuroendocrine tumors including Pheochromocytoma, Pituitary adenomas and functioning & non-functioning Islet cell and Gastrointestinal APUD tumors.
Doctor Specialty: Oncologist
Disease: Cancer
Components:
Courier Charges: 0.00
Home Collection: Available
Department:
Pre Test Information: Proton pump inhibitor medications should be discontinued for at least 2 weeks prior to sample collection.